Irinotecan for Treatment of Cancer is manufactured by Unimark Remedies Limited. Unimark Remedies Limited is an ISO 14001 and 18001 certified company that manufactures pharmacueticals like cephalosporins, carbapenems, antibacterials and antimicrobials. The company also has approvals from US FDA, EDQM and WHO. Irinotecan for Treatment of Cancer is a topoisomerase 1 inhibitor, which prevents DNA from unwinding. Chemically, it is a semisynthetic analogue of the natural alkaloid camptothecin. Its main use is in colon cancer, particularly in combination with other chemotherapy agents.