Claris lifesciences is an international most admired pharmaceutical company, in the business of manufacturing and marketing of high end injectables with focus on new drug delivery systems for treatment of critical illnesses and diseases. Claris lifesciences presents tranol. Tranol is tramadol, centrally acting synthetic opioid analgesic. Though its mode of action is not completely understood, from animal tests, at least two complementary mechanisms appear applicable: binding of parent and m1 metabolite to ยต-opioid receptors and weak inhibition of reuptake of nor epinephrine and serotonin.