Systopic Laboratories Pvt. Ltd. Manufactures Pioglitazone Composition Anti-Diabetic Drugs for Diabetes Mellitus. Systopic Laboratories Pvt. Ltd. Supplies innovative products aimed to deliver better therapeutic solutions. Pioglitazone Composition Anti-Diabetic Drugs for Diabetes Mellitus helps in decreasing insulin resistance in the periphery and in the liver resulting in increased insulin-dependent glucose disposal and decreased hepatic glucose output. Pioglitazone Composition Anti-Diabetic Drugs for Diabetes Mellitus is a potent agonist for peroxisome proliferator-activated receptor-gamma [PPAR γ]. PPAR receptors are found in tissues important for insulin action such as adipose tissue, skeletal muscle, and liver. Activation of PPAR? nuclear receptors modulates the transcription of a number of insulin responsive genes involved in the control of glucose and lipid metabolism. It is available in the brand name of Piosys. This can be available in the packet of 100 tabs/ box [10 X 10].