Systopic Laboratories Pvt. Ltd. Offers Composition of Losartan Potassium and Hydrochlorthiazide for Hypertension. Systopic Laboratories Pvt. Ltd. Manufactures innovative products aimed to deliver better therapeutic solutions. Composition of Losartan Potassium and Hydrochlorthiazide for Hypertension is used for diabetic nephropathy. Composition of Losartan Potassium and Hydrochlorthiazide for Hypertension is available in the packet of 100 tabs / box [10 x 10]. Losartan and its metabolite block the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor found in many tissues. Hydrochlorothiazide is a thiazide diuretic. It is available in the brand name of GIFTAN-HC.