Itraconazole Pellets for Fungal Infections work by preventing the fungus from growing. Itraconazole Pellets are used to treat certain types of fungal infections, both internally, inside the body and externally, skin and nails. Itraconazole Pellets go into bloodstream and travels to the source of the infection underneath the nail so that it can fight the infection there. Itraconazole Pellets can be used for the treatment of fungal infections in both HIV- and non-HIV-infected individuals. Itraconazole Pellets are active against fungal infections such as aspergillosis, blastomycosis, histoplasmosis and candidiasis, as well as fungal infection localized to the toenails and fingernails. Itraconazole Pellets are used for treating patients with fever and low white blood cell counts who are likely to develop a fungal infection. Itraconazole Pellets for Fungal Infections inhibit cytochrome P450 oxidase mediated synthesis of ergosterol.